Anti-Human CERS2 Polyclonal Antibody (HP591014)

价格:

规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HP591014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human CERS2 (Asn81-Ser128).

SP260, CERS2, LASS2, CerS2, TMSG1, Ceramide synthase 2, LAG1 longevity assurance homolog 2, Tumor metastasis-suppressor gene 1 protein, Sphingosine N-acyltransferase CERS2

Purified by antigen affinity column.

Accession号

Q96G23

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Ceramide synthase 2 (CERS2) is a ~44 kDa protein. Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very-long-chain fatty acyl-CoA (chain length C22-C27). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a non-redundant role in the synthesis of ceramides with very-long-chain fatty acids in kidney, liver and brain. Regulates the abundance of myelin-specific sphingolipids galactosylceramide and sulfatide that affects myelin sheath architecture and motor neuron functions.

1. Lahiri, S. et al. (2007) FEBS letters 581, 5289-94. PMID: 17977534

2. Laviad, EL. et al. (2008) The Journal of biological chemistry 283, 5677-84. PMID: 18165233

3. Mizutani, Y. et al. (2008) Journal of lipid research 49, 2356-64. PMID: 18541923

4. Spassieva, SD. et al. (2009) The Biochemical journal 424, 273-83. PMID: 19728861

5. Ohno, Y. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 18439-44. PMID: 20937905

6. Tidhar, R. et al. (2012) The Journal of biological chemistry 287, 3197-206. PMID: 22144673

7. Kim, HJ. et al. (2012) Journal of lipid research 53, 1701-7. PMID: 22661289

8. Sassa, T. et al. (2016) The Journal of biological chemistry 291, 7477-87. PMID: 26887952

9. Tidhar, R. et al. (2018) The Journal of biological chemistry 293, 9912-9921. PMID: 29632068

For research use only.

产品说明书

Anti-Human CERS2 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CERS2 Polyclonal Antibody (HP591014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CERS2 Polyclonal Antibody (HP591014)

概述

图片

参考文献

产品说明书

相关产品推荐

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