Anti-Human Connexin 43/GJA1 Recombinant Antibody (SAA0823) (HB620023)

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50ug
100ug
1mg

数量：

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概述
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参考文献
产品说明书

概述

货号

HB620023

品牌

abinScience

描述

Anti-Human CX43/GJA1 Recombinant Antibody (SAA0823) (HB620023) is a mouse monoclonal antibody detecting CX43/GJA1 in ELISA, SPR. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, SPR

宿主

Mouse

克隆类型

Monoclonal

同种型

IgG2a

克隆号

SAA0823

靶标

GJAL, Connexin-43, GJA1, Cx43, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P17302

RRID

Anti-Human CX43/GJA1 Antibody (SAA0823) (abinScience Cat# HB620023, RRID:AB_3726345)
_x005F_x000D_

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

背景

Gap junction alpha-1 protein (CX43/GJA1) is a ~43 kDa protein. Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph (Probable). Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in the conductive system of ventricular myocardium and heart morphogenesis.

1. Ablasser, A. et al. (2013) Nature 503, 530-4. PMID: 24077100

2. Pépin, G. et al. (2020) mBio 11. PMID: 31992625

3. Huai, W. et al. (2025) Immunity 58, 797-810.e6. PMID: 40010341

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human CX43/GJA1 Antibody (SAA0823)

参考文献

产品说明书

Anti-Human Connexin 43/GJA1 Recombinant Antibody (SAA0823).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Connexin 43/GJA1 Recombinant Antibody (SAA0823) (HB620023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Connexin 43/GJA1 Recombinant Antibody (SAA0823) (HB620023)

概述

图片

参考文献

产品说明书

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