Anti-CX43/GJA1 Polyclonal Antibody (HB620014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HB620014

品牌

abinScience

描述

Anti-CX43/GJA1 Polyclonal Antibody (HB620014) is a rabbit polyclonal antibody detecting GJA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Dog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CX43/GJA1 (Phe232-Ile382).

靶标

GJAL, Connexin-43, GJA1, Cx43, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein

纯化方式

Purified by antigen affinity column.

Accession号

P17302

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Gap junction alpha-1 protein (CX43/GJA1) is a ~43 kDa protein. Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph (Probable). Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in the conductive system of ventricular myocardium and heart morphogenesis.

1. Ablasser, A. et al. (2013) Nature 503, 530-4. PMID: 24077100

2. Pépin, G. et al. (2020) mBio 11. PMID: 31992625

3. Huai, W. et al. (2025) Immunity 58, 797-810.e6. PMID: 40010341

Note

For research use only.

图片

参考文献

产品说明书

Anti-CX43/GJA1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CX43/GJA1 Polyclonal Antibody (HB620014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CX43/GJA1 Polyclonal Antibody (HB620014)

概述

图片

参考文献

产品说明书

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