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Anti-Human COMP Recombinant Antibody (SAA1641) (HW810013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HW810013
品牌abinScience
种属反应性Human
应用ELISA
同种型IgG2a, kappa
克隆号SAA1641
靶标TSP5, Thrombospondin-5, COMP, Cartilage oligomeric matrix protein
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P49747
RRIDAnti-Human COMP Antibody (SAA1641) (abinScience Cat# HW810013, RRID:AB_3727402)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Cartilage oligomeric matrix protein (COMP) is a ~82 kDa protein. Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP).

1. Chen, FH. et al. (2005) The Journal of biological chemistry 280, 32655-61. PMID: 16051604
2. Koelling, S. et al. (2006) Arthritis research & therapy 8, R56. PMID: 16542502
3. Gagarina, V. et al. (2008) The Journal of biological chemistry 283, 648-659. PMID: 17993464
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human COMP Antibody (SAA1641)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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