

| 货号 | HW810013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1641 | ||||
| 靶标 | TSP5, Thrombospondin-5, COMP, Cartilage oligomeric matrix protein | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P49747 | ||||
| RRID | Anti-Human COMP Antibody (SAA1641) (abinScience Cat# HW810013, RRID:AB_3727402) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Cartilage oligomeric matrix protein (COMP) is a ~82 kDa protein. Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). 1. Chen, FH. et al. (2005) The Journal of biological chemistry 280, 32655-61. PMID: 16051604 2. Koelling, S. et al. (2006) Arthritis research & therapy 8, R56. PMID: 16542502 3. Gagarina, V. et al. (2008) The Journal of biological chemistry 283, 648-659. PMID: 17993464 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human COMP Antibody (SAA1641)



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