Anti-COMP Polyclonal Antibody (HW810014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HW810014

品牌

abinScience

描述

Anti-COMP Polyclonal Antibody (HW810014) is a rabbit polyclonal antibody detecting COMP in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human COMP (Ser123-His240).

靶标

TSP5, Thrombospondin-5, COMP, Cartilage oligomeric matrix protein

纯化方式

Purified by antigen affinity column.

Accession号

P49747

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cartilage oligomeric matrix protein (COMP) is a ~82 kDa protein. Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP).

1. Chen, FH. et al. (2005) The Journal of biological chemistry 280, 32655-61. PMID: 16051604

2. Koelling, S. et al. (2006) Arthritis research & therapy 8, R56. PMID: 16542502

3. Gagarina, V. et al. (2008) The Journal of biological chemistry 283, 648-659. PMID: 17993464

Note

For research use only.

图片

参考文献

产品说明书

Anti-COMP Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-COMP Polyclonal Antibody (HW810014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-COMP Polyclonal Antibody (HW810014)

概述

图片

参考文献

产品说明书

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