Anti-Human LRP8 Recombinant Antibody (SAA1673) (HC675013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HC675013

abinScience

种属反应性

Human

ELISA

IgG2a, kappa

SAA1673

LRP8, LRP-8, Low-density lipoprotein receptor-related protein 8, APOER2, Apolipoprotein E receptor 2

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q14114

Anti-Human LRP8 Antibody (SAA1673) (abinScience Cat# HC675013, RRID:AB_3727434)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Low-density lipoprotein receptor-related protein 8 (LRP8) is a ~105 kDa protein. Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development.

1. Andersen, OM. et al. (2003) Biochemistry 42, 9355-64. PMID: 12899622

2. Li, X. et al. (2003) Biochemistry 42, 10406-17. PMID: 12950167

3. Yasui, N. et al. (2010) Structure (London, England : 1993) 18, 320-31. PMID: 20223215

4. Dlugosz, P. et al. (2019) Frontiers in molecular neuroscience 12, 53. PMID: 30873003

5. Lutters, BC. et al. (2003) The Journal of biological chemistry 278, 33831-8. PMID: 12807892

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human LRP8 Antibody (SAA1673)

产品说明书

Anti-Human LRP8 Recombinant Antibody (SAA1673).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LRP8 Recombinant Antibody (SAA1673) (HC675013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LRP8 Recombinant Antibody (SAA1673) (HC675013)

概述

图片

参考文献

产品说明书

相关产品推荐

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