Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937) (HB250013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HB250013

abinScience

种属反应性

Human

ELISA

IgG2a, kappa

SAA1937

94 kDa glucose-regulated protein, HSP90B1, gp96 homolog, GRP94, Heat shock protein 90 kDa beta member 1, Endoplasmin, TRA1, Tumor rejection antigen 1, GRP-94

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P14625

Anti-Human HSP90B1/GRP94 Antibody (SAA1937) (abinScience Cat# HB250013, RRID:AB_3727701)
_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Endoplasmin (HSP90B1/GRP94) is a ~92 kDa protein. ATP-dependent chaperone involved in the processing of proteins in the endoplasmic reticulum, regulating their transport. Together with MESD, acts as a modulator of the Wnt pathway by promoting the folding of LRP6, a coreceptor of the canonical Wnt pathway. When associated with CNPY3, required for proper folding of Toll-like receptors. Promotes folding and trafficking of TLR4 to the cell surface. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.

1. Liu, B. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 6877-82. PMID: 23572575

2. Ma, M. et al. (2024) Science (New York, N.Y.) 386, 667-672. PMID: 39509507

3. Randow, F. et al. (2001) Nature cell biology 3, 891-6. PMID: 11584270

4. Zhang, M. et al. (2020) Cell 181, 637-652.e15. PMID: 32272059

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human HSP90B1/GRP94 Antibody (SAA1937)

产品说明书

Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937) (HB250013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HSP90B1/GRP94 Recombinant Antibody (SAA1937) (HB250013)

概述

图片

参考文献

产品说明书

相关产品推荐

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