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Research Grade Efprezimod alfa (HB630036)

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概述
货号HB630036
品牌abinScience
描述
Research Grade Efprezimod alfa (HB630036) is a human monoclonal antibody detecting Signal transducer CD24 in FuncS. Suitable for Human.
种属反应性Human
应用FuncS
宿主Human
克隆类型Monoclonal
同种型Fusion - [CD24 (CD24 molecule, CD24 antigen (small cell lung carcinoma cluster 4 antigen))]2 - IGHG1 Fc
靶标Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24, CD24A
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P25063
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Signal transducer CD24 (Siglec-10) is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.

1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396
NoteFor research use only.
Isotype ControlVHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2) (ZP167307)
图片

  • SDS-PAGE

    SDS-PAGE for Research Grade Efprezimod alfa

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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