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Anti-SERPINE1/PAI-1 Polyclonal Antibody (ARO-A11701)

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概述
货号ARO-A11701
品牌ProteoGenix
描述
Anti-SERPINE1/PAI-1 Polyclonal Antibody (ARO-A11701) is a rabbit polyclonal antibody detecting PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1 in ELISA, IHC, WB. Suitable for Human, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SERPINE1/PAI-1 (Gly21-Pro402).
靶标PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1
纯化方式Purified by antigen affinity column.
Accession号P05121
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Plasminogen activator inhibitor 1 (SERPINE1/PAI-1) is a ~45 kDa protein. Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.

1. Szabo, R. et al. (2005) The Biochemical journal 390, 231-42. PMID: 15853774
2. Jankun, J. et al. (2007) International journal of molecular medicine 20, 683-7. PMID: 17912461
3. Lee, MH. et al. (1993) Blood 81, 2357-62. PMID: 8481516
4. Fay, WP. et al. (1997) Blood 90, 204-8. PMID: 9207454
5. Anisuzzaman et al. (2011) Biochemical and biophysical research communications 413, 599-604. PMID: 21925150
6. Planus, E. et al. (1997) Journal of cell science 110 ( Pt 9), 1091-8. PMID: 9175705
7. Degryse, B. et al. (2004) The Journal of biological chemistry 279, 22595-604. PMID: 15001579
8. Kjøller, L. et al. (1997) Experimental cell research 232, 420-9. PMID: 9168821
9. Providence, KM. et al. (2008) Archives of dermatological research 300, 303-10. PMID: 18386027
10. Kortlever, RM. et al. (2006) Nature cell biology 8, 877-84. PMID: 16862142
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-SERPINE1/PAI-1 Polyclonal Antibody

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