Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody (JN930024)

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概述
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参考文献
产品说明书

概述

货号

JN930024

品牌

abinScience

描述

Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody (JN930024) is a rabbit polyclonal antibody detecting Isocitrate lyase. Suitable for Mycobacterium tuberculosis and Mycobacterium bovis.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Mycobacterium tuberculosis, Mycobacterium bovis

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mycobacterium tuberculosis Isocitrate lyase/ICL (Met1-His428).

靶标

EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P9WKK7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Isocitrate lyase (ICL) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route).

1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251

2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599

3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086

4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272

Note

For research use only

图片

参考文献

产品说明书

Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody (JN930024)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody (JN930024)

概述

图片

参考文献

产品说明书

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