Anti-ARG2 Polyclonal Antibody (HX072014)

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概述
图片
参考文献
产品说明书

概述

货号

HX072014

品牌

abinScience

描述

Anti-ARG2 Polyclonal Antibody (HX072014) is a rabbit polyclonal antibody detecting ARG2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human ARG2 (Val23-Ile354).

靶标

Arginase-2, mitochondrial, Type II arginase, Kidney-type arginase, Arginase II, Non-hepatic arginase, ARG2

纯化方式

Purified by antigen affinity column.

Accession号

P78540

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Arginase-2, mitochondrial (ARG2/Arginase II) is a ~38 kDa protein. May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium.

1. Geiger, R. et al. (2016) Cell 167, 829-842.e13. PMID: 27745970

2. Xu, W. et al. (2016) The Journal of clinical investigation 126, 2465-81. PMID: 27214549

3. McGovern, N. et al. (2017) Nature 546, 662-666. PMID: 28614294

4. Yepuri, G. et al. (2012) Aging cell 11, 1005-16. PMID: 22928666

5. Xiong, Y. et al. (2014) Autophagy 10, 2223-38. PMID: 25484082

6. Xiong, Y. et al. (2013) Journal of the American Heart Association 2, e000096. PMID: 23832324

7. Cama, E. et al. (2003) Biochemistry 42, 8445-51. PMID: 12859189

Note

For research use only.

图片

Western blot

Lane 1: K562 cell lysate
Lane 2: 293T cell lysate

参考文献

产品说明书

Anti-ARG2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ARG2 Polyclonal Antibody (HX072014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ARG2 Polyclonal Antibody (HX072014)

概述

图片

参考文献

产品说明书

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