Anti-Human CD276/B7-H3 Recombinant Antibody (Mab 8H9) (HV612207)

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100ug

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货号	HV612207
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	Mab 8H9
经测试应用	FCM
靶标	CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q5ZPR3
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	CD276 antigen (B7-H3) is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. CD276 is the therapeutic target of omburtamab (clinical).
Note	For research use only.

Flow Cytometry

Flow-cytometry using anti-human CD276 antibody.293T cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD276 antibody monoclonal antibody (Catalog # HV612207 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human CD276 antibody.PC-3 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD276 antibody monoclonal antibody (Catalog # HV612207 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human CD276/B7-H3 Recombinant Antibody (Mab 8H9).pdf

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Anti-Human CD276/B7-H3 Recombinant Antibody (Mab 8H9) (HV612207)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD276/B7-H3 Recombinant Antibody (Mab 8H9) (HV612207)

概述

图片

参考文献

产品说明书

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