Anti-Human Glypican 3 Recombinant Antibody (SAA0134) (HW310107)

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货号	HW310107
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM, WB
同种型	IgG1, kappa
克隆号	SAA0134
靶标	GPC3, MXR7, GTR2-2, Glypican-3, Intestinal protein OCI-5, OCI5
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P51654
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Glypican-3 (GPC3/Glypican 3) is a ~65 kDa protein. Cell surface proteoglycan. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway. 1. De Cat, B. et al. (2003) The Journal of cell biology 163, 625-35. PMID: 14610063 2. Capurro, MI. et al. (2005) The Journal of biological chemistry 280, 41201-6. PMID: 16227623 3. Capurro, M. et al. (2014) Journal of cell science 127, 1565-75. PMID: 24496449 4. Davoodi, J. et al. (2007) Proteomics 7, 2300-10. PMID: 17549790
Note	For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human GPC3 Antibody (SAA0134)

产品说明书

Anti-Human Glypican 3 Recombinant Antibody (SAA0134).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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Anti-Human Glypican 3 Recombinant Antibody (SAA0134) (HW310107)

概述

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参考文献

产品说明书

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重组蛋白

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实验相关试剂

Anti-Human Glypican 3 Recombinant Antibody (SAA0134) (HW310107)

概述

图片

参考文献

产品说明书

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