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Research Grade Codrituzumab (HW310016)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述
  • 图片
  • 参考文献
  • 产品说明书
概述
货号HW310016
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Humanized
同种型IgG1-kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标GPC3, MXR7, GTR2-2, Glypican-3, Intestinal protein OCI-5, OCI5
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P51654
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名GC33, RG7686, RO5137382, 1365267-33-9
背景Codrituzumab (GC33) is a humanized monoclonal antibody targeting human GPC3 (glypican-3), with high affinity (Kd of 0.673 nM). GPC3 is an oncofetal protein expressed on the cell surface of hepatocellular carcinoma (HCC). Codrituzumab induces antibody-dependent cellular cytotoxicity (ADCC) and inhibits tumor growth.
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Codrituzumab.

  • Bioactivity

    Detects GPC3 in indirect ELISAs.

参考文献

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