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Anti-Human CD133 Recombinant Antibody (SAA0409) (HT495207)

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  • 100ug
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概述
货号HT495207
品牌abinScience
种属反应性Human
应用FCM
同种型IgG1, kappa
克隆号SAA0409
靶标PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O43490
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Prominin-1 (CD133/PROM1) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617
2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CD133/PROM1 Antibody (SAA0409)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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