

| 货号 | HT495016 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Anti-Human CD133/PROM1 (CMab-43) (HT495016) is a research-grade recombinant antibody targeting CD133. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG |
| 克隆号 | CMab-43 |
| 表达系统 | Mammalian cells |
| 克隆类型 | Monoclonal |
| 靶标 | PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1 |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | O43490 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | CMab-43, CMab43, CMab43 |
| 背景 | Prominin-1 (CD133/PROM1) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. 1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617 2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human CD133/PROM1 (CMab-43)



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