Anti-Human CD48/SLAMF2 Recombinant Antibody (SAA0017), FITC (HY573117)

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货号	HY573117
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM, WB
宿主	Human
同种型	IgG1
克隆号	SAA0017
偶联物	FITC
克隆类型	Monoclonal
靶标	Signaling lymphocytic activation molecule 2, TCT.1, CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1, CD48, BLAST1, Leukocyte antigen MEM-102, SLAMF2, BCM1 surface antigen, SLAM family member 2, RHC39801
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Accession号	P09326
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	CD48 antigen is a ~27 kDa protein. Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including CD244/2B4 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells. 1. Hawash, IY. et al. (2002) Biochimica et biophysica acta 1589, 140-50. PMID: 12007789 2. Muhammad, A. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 7672-80. PMID: 19494291 3. Claus, M. et al. (2016) Open biology 6. PMID: 27249817 4. Brown, MH. et al. (1998) The Journal of experimental medicine 188, 2083-90. PMID: 9841922
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human CD48/SLAMF2 Recombinant Antibody (SAA0017), FITC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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Anti-Human CD48/SLAMF2 Recombinant Antibody (SAA0017), FITC (HY573117)

概述

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参考文献

产品说明书

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重组蛋白

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实验相关试剂

Anti-Human CD48/SLAMF2 Recombinant Antibody (SAA0017), FITC (HY573117)

概述

图片

参考文献

产品说明书

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