Anti-Human CD48/SLAMF2 Recombinant Antibody (156-4H9) (HY573207)

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50ug
100ug

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货号	HY573207
品牌	abinScience
种属反应性	Human
应用	FCM, Neutralization
同种型	IgG1, kappa
克隆号	156-4H9
靶标	Signaling lymphocytic activation molecule 2, TCT.1, CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1, CD48, BLAST1, Leukocyte antigen MEM-102, SLAMF2, BCM1 surface antigen, SLAM family member 2
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P09326
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	CD48 antigen is a ~27 kDa protein. Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including CD244/2B4 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells. 1. Hawash, IY. et al. (2002) Biochimica et biophysica acta 1589, 140-50. PMID: 12007789 2. Muhammad, A. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 7672-80. PMID: 19494291 3. Claus, M. et al. (2016) Open biology 6. PMID: 27249817 4. Brown, MH. et al. (1998) The Journal of experimental medicine 188, 2083-90. PMID: 9841922
Note	For research use only.

Western blot

Western blot analysis was performed using anti-CD48 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD48 (Catalog No: HY573021)
Lane 2: negative control
Bioactivity

Detects recombinant CD48 (Catalog No: HY573021) in indirect ELISA.

产品说明书

Anti-Human CD48/SLAMF2 Recombinant Antibody (156-4H9).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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Anti-Human CD48/SLAMF2 Recombinant Antibody (156-4H9) (HY573207)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD48/SLAMF2 Recombinant Antibody (156-4H9) (HY573207)

概述

图片

参考文献

产品说明书

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