Anti-Human Axl Recombinant Antibody (SAA0127), FITC (HB709117)

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货号	HB709117
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG1, kappa
克隆号	SAA0127
偶联物	FITC
克隆类型	Monoclonal
靶标	UFO, AXL oncogene, Tyrosine-protein kinase receptor UFO, AXL
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Accession号	P30530
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Tyrosine-protein kinase receptor UFO (AXL) is a ~98 kDa protein. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of AXL. Following activation by ligand, AXL binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1, PIK3R2 and PIK3R3; but also GRB2, PLCG1, LCK and PTPN11. Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TNS2. Recruitment of GRB2 and phosphatidylinositol 3 kinase regulatory subunits by AXL leads to the downstream activation of the AKT kinase.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human Axl Recombinant Antibody (SAA0127), FITC.pdf

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Anti-Human Axl Recombinant Antibody (SAA0127), FITC (HB709117)

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产品说明书

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Anti-Human Axl Recombinant Antibody (SAA0127), FITC (HB709117)

概述

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参考文献

产品说明书

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