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Anti-Human CD275/ICOSLG Antibody (SAA0089), APC (ARO-A10460)

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概述
货号ARO-A10460
品牌ProteoGenix
描述
Anti-Human CD275/ICOSLG Antibody (SAA0089), APC [SAA0089] (ARO-A10460) is a human monoclonal antibody detecting B7RP1, B7-related protein 1, CD275, ICOSL, ICOSLG, KIAA0653, B7 homolog 2, ICOS ligand, B7RP-1, B7H2, B7-H2, B7-like protein Gl50 in FCM. Suitable for Human.
Highlights
  • Validated for FCM — Optimized for consistent performance.
种属反应性Human
应用FCM
宿主Human
同种型IgG2, kappa
克隆号SAA0089
偶联物APC
克隆类型Monoclonal
靶标B7RP1, B7-related protein 1, CD275, ICOSL, ICOSLG, KIAA0653, B7 homolog 2, ICOS ligand, B7RP-1, B7H2, B7-H2, B7-like protein Gl50
内毒素水平Please contact with the lab for this information.
Accession号O75144
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

ICOS ligand (CD275/ICOSLG) is a ~33 kDa protein. Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion. Also induces B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. In endothelial cells, required for proper neutrophil transmigration in response to chemoattractants, such as CXCL8/IL8 or N-formyl-methionyl peptides (fMLP).

1. Yoshinaga, SK. et al. (2000) International immunology 12, 1439-47. PMID: 11007762
2. Wang, S. et al. (2000) Blood 96, 2808-13. PMID: 11023515
3. Roussel, L. et al. (2018) The Journal of experimental medicine 215, 3151-3164. PMID: 30498080
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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