

| 货号 | ARO-A10976 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human CD133/PROM1 Antibody (SAA0050), FITC [SAA0050] (ARO-A10976) is a human monoclonal antibody detecting PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1 in FCM. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | FCM |
| 宿主 | Human |
| 同种型 | IgG1 |
| 克隆号 | SAA0050 |
| 偶联物 | FITC |
| 克隆类型 | Monoclonal |
| 靶标 | PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1 |
| 内毒素水平 | Please contact with the lab for this information. |
| Accession号 | O43490 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Prominin-1 (CD133/PROM1) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. 1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617 2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439 |
| Note | For research use only. |

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