Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE (HV375127)

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货号	HV375127
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG4, kappa
克隆号	SAA0087
偶联物	PE
克隆类型	Monoclonal
靶标	B- and T-lymphocyte attenuator, BTLA, CD272, B- and T-lymphocyte-associated protein
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), PE
Accession号	Q7Z6A9
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	B- and T-lymphocyte attenuator (CD272/BTLA) is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. _x005F_x000D_ _x005F_x000D_ 1. Watanabe, N. et al. (2003) Nature immunology 4, 670-9. PMID: 12796776 _x005F_x000D_ _x005F_x000D_ 2. Gavrieli, M. et al. (2003) Biochemical and biophysical research communications 312, 1236-43. PMID: 14652006 _x005F_x000D_ _x005F_x000D_ 3. Sedy, JR. et al. (2005) Nature immunology 6, 90-8. PMID: 15568026 _x005F_x000D_ _x005F_x000D_ 4. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050 _x005F_x000D_ _x005F_x000D_ 5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Flow cytometry

Flow-cytometry PE using anti-human CD272 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human CD272 monoclonal antibody (Catalog HV375127) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE.pdf

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Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE (HV375127)

概述

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参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

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实验相关试剂

Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE (HV375127)

概述

图片

参考文献

产品说明书

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