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Anti-Tocilizumab ELISA Kit (AY583018)

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规格:
  • 96T
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号AY583018
品牌abinScience
描述
Anti-Tocilizumab ELISA Kit (AY583018) — Quantitative sandwich ELISA for Anti-Tocilizumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • Ready-to-Use — Complete kit with pre-coated plates included.
样本类型Plasma, Serum
灵敏度0.57 ng/ml
检测范围1.56-100 ng/ml
Accession号P08887
应用ELISA
检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
稳定性和存储The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
规格

Tocilizumab

别名Atlizumab, MRA / R-1569 / RHPM-1 / RO-4877533, 375823-41-9
背景

Interleukin-6 receptor subunit alpha (Tocilizumab) is a ~51 kDa protein. Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling', the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system.

1. Larsen, JV. et al. (2017) Molecular and cellular biology 37. PMID: 28265003
2. Kang, S. et al. (2019) Immunity 50, 1007-1023. PMID: 30995492
3. Spencer, S. et al. (2019) The Journal of experimental medicine 216, 1986-1998. PMID: 31235509
NoteFor Research Use Only.
图片
  • Standard Curve

    Standard Curve of Anti-Tocilizumab ELISA Kit

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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