货号 | HY583016 |
---|---|
品牌 | abinScience |
种属反应性 | Human |
应用 | Research Grade Biosimilar |
宿主 | Human |
同种型 | IgG1-kappa |
表达系统 | Mammalian Cells |
克隆类型 | Monoclonal |
靶标 | sIL6R, Interleukin-6 receptor subunit alpha, CD126, IL-6R 1, IL-6R subunit alpha, Membrane glycoprotein 80, gp80, IL6R, IL-6RA, IL-6 receptor subunit alpha, IL-6R-alpha |
内毒素水平 | Please contact the lab for this information. |
纯度 | >95% purity as determined by SDS-PAGE. |
纯化方式 | Protein A/G, purified from cell culture supernatant. |
Accession号 | P08887 |
状态 | Liquid |
保存溶液 | 0.01M PBS,pH7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
别名 | REGN88,SAR153191,CAS:1189541-98-7 |
背景 | Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis. |
Note | For research use only. Not for use in clinical or therapeutic applications. |
SEC-HPLC detection for Research Grade Sarilumab.
Detects Human CD126/IL6R/IL-6RA in indirect ELISAs.
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