Anti-Human CD277/BTN3A1 Reference Antibody (CTX 2026, RUO) (HT139016)

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100ug
1mg
5mg
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50mg
100mg

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概述
图片
参考文献
产品说明书

HT139016

abinScience

种属反应性

Human

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Human

CTX 2026

CTX-2026 (1 ug/mL; 12 h) redirects the cytotoxic activity of Vγ9Vδ2 T cells from multiple donors against BTN3A1 + OVCAR3 cells or primary HGSOC cells [1]. CTX-2026 (1 ug/mL; 6 d) shows a rescuing effect on nonablated CD45 + T cells [1]. CTX-2026 (5 mg/kg; i.p. for 15 days every 3 days once) effects the tumor growth of NY-OVCAR3 tumor mice [1].

Mammalian cells

Monoclonal

BTF5, BTN3A1, Butyrophilin subfamily 3 member A1, CD277

内毒素水平

< 10 EU/mg

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O00481

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

CTX-2026

Butyrophilin subfamily 3 member A1 (CD277/BTN3A1) is a ~57 kDa protein. Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

1. Payne KK, et al. BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells. Science. 2020 Aug 21;369(6506):942-949. [HT139016]

For research use only. Not suitable for clinical or therapeutic use.

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD277/BTN3A1 Antibody (CTX 2026)

产品说明书

Anti-Human CD277/BTN3A1 Reference Antibody (CTX 2026, RUO).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD277/BTN3A1 Reference Antibody (CTX 2026, RUO) (HT139016)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD277/BTN3A1 Reference Antibody (CTX 2026, RUO) (HT139016)

概述

图片

参考文献

产品说明书

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