Anti-HIV-1 gp120 120 Reference Antibody (VRC01LS, RUO) (VK617066)

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货号	VK617066
品牌	abinScience
种属反应性	Human immunodeficiency virus type 1 (HIV-1)
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG
克隆号	VRC01LS
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	gp120/Glycoprotein 120
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q03805
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	VRC01LS
背景	Envelope glycoprotein gp160 (gp120/Glycoprotein 120) is a ~96 kDa protein. Envelope glycoprotein gp160: Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.
文献	1. Happe M, et al. Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection. JCI Insight. 2025 Feb 24;10(4):e181496. [VK617066] 2. Gaudinski MR, et al. Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults. PLoS Med. 2018 Jan 24;15(1):e1002493. [VK617066]
Note	For research use only. Not suitable for clinical or therapeutic use.

Bioactivity

Detects recombinant HIV1 gp120 (Catalog No: VK617011) in indirect ELISA.
Bioactivity

Detects recombinant HIV1 gp120 (Catalog No: VK617021) in indirect ELISA.

产品说明书

Anti-HIV-1 gp120 120 Reference Antibody (VRC01LS, RUO).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-HIV-1 gp120 120 Reference Antibody (VRC01LS, RUO) (VK617066)

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参考文献

产品说明书

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实验相关试剂

Anti-HIV-1 gp120 120 Reference Antibody (VRC01LS, RUO) (VK617066)

概述

图片

参考文献

产品说明书

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