Anti-HIV-1 gp120 Reference Antibody (mD1.22, RUO) (VK617106)

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概述
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参考文献
产品说明书

概述

货号

VK617106

品牌

abinScience

描述

Anti-HIV1 gp120/Glycoprotein 120 Antibody (mD1.22) (VK617106) is a research-grade recombinant antibody targeting CD4. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Human immunodeficiency virus type 1 (HIV-1)

应用

ELISA, Functional assay, Research in vivo

宿主

Human

同种型

Fusion - [CD4 (LFA3, lymphocyte function associated antigen 3)]2 - IGHG1 Fc (Fragment constant)

克隆号

mD1.22

表达系统

Mammalian cells

克隆类型

Monoclonal

靶标

T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, CD4

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P01730

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

T-cell surface glycoprotein CD4 (gp120/Glycoprotein 120) is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

Note

For research use only. Not suitable for clinical or therapeutic use.

图片

参考文献

产品说明书

Anti-HIV-1 gp120 Reference Antibody (mD1.22, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-HIV-1 gp120 Reference Antibody (mD1.22, RUO) (VK617106)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-HIV-1 gp120 Reference Antibody (mD1.22, RUO) (VK617106)

概述

图片

参考文献

产品说明书

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