Anti-Human BTLA/CD272 Reference Antibody (Radanstobart, RUO) (HV375076)

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概述
图片
参考文献
产品说明书

概述

货号

HV375076

品牌

abinScience

描述

Research Grade radanstobart (HV375076) is a human monoclonal antibody. Suitable for Human.

种属反应性

Human

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

宿主

Human

同种型

IgG4, kappa

克隆类型

Monoclonal

内毒素水平

< 10 EU/mg

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

Q7Z6A9

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

B- and T-lymphocyte attenuator (CD272/BTLA) is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells.

1. Watanabe, N. et al. (2003) Nature immunology 4, 670-9. PMID: 12796776

2. Gavrieli, M. et al. (2003) Biochemical and biophysical research communications 312, 1236-43. PMID: 14652006

3. Sedy, JR. et al. (2005) Nature immunology 6, 90-8. PMID: 15568026

4. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050

5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human BTLA/CD272 Reference Antibody (Radanstobart, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BTLA/CD272 Reference Antibody (Radanstobart, RUO) (HV375076)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BTLA/CD272 Reference Antibody (Radanstobart, RUO) (HV375076)

概述

图片

参考文献

产品说明书

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