Human BTLA/CD272 Recombinant Protein (C-Fc) (HV375021)

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100ug
1mg

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概述

货号	HV375021
品牌	abinScience
描述	Recombinant Human BTLA Protein, C-Fc (HV375021) expressed in Mammalian Cells, spanning Met1-Ser150. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	Mammalian cells
Accession号	Q7Z6A9
蛋白长度	Met1-Ser150
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	43.65 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, BTLA, CD272
背景	B- and T-lymphocyte attenuator is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. 1. Watanabe, N. et al. (2003) Nature immunology 4, 670-9. PMID: 12796776 2. Gavrieli, M. et al. (2003) Biochemical and biophysical research communications 312, 1236-43. PMID: 14652006 3. Sedy, JR. et al. (2005) Nature immunology 6, 90-8. PMID: 15568026 4. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050 5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044
Note	For research use only

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Bioactivity

Immobilized HV375021 Human BTLA Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind HV480011 Human CD270/TNFRSF14 Recombinant Protein (C-His), the EC 50 is 15.2 μg/mL.
Bioactivity

Immobilized HV375021 Human BTLA Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind MV480011 Mouse CD270/TNFRSF14 Recombinant Protein (C-Fc), the EC 50 is 251 ng/mL.

参考文献

产品说明书

Human BTLA/CD272 Recombinant Protein (C-Fc).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Human BTLA/CD272 Recombinant Protein (C-Fc) (HV375021)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Human BTLA/CD272 Recombinant Protein (C-Fc) (HV375021)

概述

图片

参考文献

产品说明书

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