Anti-Human Serpin E1/PAI-1 Recombinant Nanobody (SAA1078) (HY185033)

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50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HY185033

品牌

abinScience

描述

Anti-Human SERPINE1/PAI-1 Nanobody (SAA1078) [SAA1078] (HY185033) is a alpaca monoclonal antibody detecting SERPINE1 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

克隆类型

Monoclonal

同种型

VHH-8His-Cys-tag

克隆号

SAA1078

靶标

PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

P05121

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Plasminogen activator inhibitor 1 (SERPINE1/PAI-1) is a ~45 kDa protein. Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.

1. Szabo, R. et al. (2005) The Biochemical journal 390, 231-42. PMID: 15853774

2. Jankun, J. et al. (2007) International journal of molecular medicine 20, 683-7. PMID: 17912461

3. Lee, MH. et al. (1993) Blood 81, 2357-62. PMID: 8481516

4. Fay, WP. et al. (1997) Blood 90, 204-8. PMID: 9207454

5. Anisuzzaman et al. (2011) Biochemical and biophysical research communications 413, 599-604. PMID: 21925150

6. Planus, E. et al. (1997) Journal of cell science 110 ( Pt 9), 1091-8. PMID: 9175705

7. Degryse, B. et al. (2004) The Journal of biological chemistry 279, 22595-604. PMID: 15001579

8. Kjøller, L. et al. (1997) Experimental cell research 232, 420-9. PMID: 9168821

9. Providence, KM. et al. (2008) Archives of dermatological research 300, 303-10. PMID: 18386027

10. Kortlever, RM. et al. (2006) Nature cell biology 8, 877-84. PMID: 16862142

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human SERPINE1/PAI-1 Nanobody (SAA1078)
Bioactivity

Detects recombinant SERPINE1 (Catalog No: HY185012) in indirect ELISA.

参考文献

产品说明书

Anti-Human Serpin E1/PAI-1 Recombinant Nanobody (SAA1078).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Serpin E1/PAI-1 Recombinant Nanobody (SAA1078) (HY185033)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Serpin E1/PAI-1 Recombinant Nanobody (SAA1078) (HY185033)

概述

图片

参考文献

产品说明书

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