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Science Advances

Researchers identify pathway that enables regulatory T cells to prevent devastating autoimmune responses to gut bacteria

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Nature Reviews Immunology

Interleukin-33 and its receptor: multifaceted roles and emerging therapeutic potential

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Science Advances

Researchers identify pathway that enables regulatory T cells to prevent devastating autoimmune responses to gut bacteria

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Science Immunology

AMnESTI reverses age-associated lung immune decline to drive heterosubtypic protection by inactivated influenza vaccines

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Cell

Lifestyle-induced regulatory T cell fragility primes adverse events after immune checkpoint blockade

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Cancer Cell

Tumor immune microenvironment remodeling predicts response to checkpoint inhibitor therapy

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Immunity

A distinct effector B cell population drives autoantibody production in SARS-CoV-2 infection

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Science

Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species

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Journal of Experimental Medicine

Epitope-diverse autoantibodies induce neutrophil–epithelial niches driving kidney injury in ANCA-associated glomerulonephritis

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Nature Medicine

Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade

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Science Translational Medicine

IL-21 and CXCR6+ CD8+ T cells drive checkpoint inhibitor-associated thyroid autoimmunity

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Nature Immunology

IL-2-producing TFH cells sustain Treg cell homeostasis and immune tolerance in the gut

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Nature

Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism

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Cancer Cell

Tumor immune microenvironment remodeling predicts response to checkpoint inhibitor therapy

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Nature Biotechnology

Reprogrammed NK immune cells target cancer and autoimmune disorders

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