Anti-Human CALCR/Calcitonin receptor/CT-R Recombinant Antibody (SAA1757) (HB973013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HB973013

abinScience

种属反应性

Human

ELISA

IgG2a, kappa

SAA1757

CT-R, CALCR, Calcitonin receptor

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P30988

Anti-Human CALCR/Calcitonin receptor/CT-R Antibody (SAA1757) (abinScience Cat# HB973013, RRID:AB_3727518)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Calcitonin receptor (CALCR/CT-R) is a ~55 kDa protein. G protein-coupled receptor activated by ligand peptides amylin (IAPP), calcitonin (CT/CALCA) and calcitonin gene-related peptide type 1 (CGRP1/CALCA). CALCR interacts with receptor-activity-modifying proteins RAMP1, 2 and 3 to form receptor complexes AMYR1, 2 and 3, respectively. IAPP, CT and CGRP1 activate CALCR and AMYRs with distinct modes of receptor activation resulting in specific phenotypes. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway.

1. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283

2. Cao, J. et al. (2024) Biochemistry 63, 1089-1096. PMID: 38603770

3. Moore, EE. et al. (1995) Molecular endocrinology (Baltimore, Md.) 9, 959-68. PMID: 7476993

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human CALCR/Calcitonin receptor/CT-R Antibody (SAA1757)

产品说明书

Anti-Human CALCR/Calcitonin receptor/CT-R Recombinant Antibody (SAA1757).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CALCR/Calcitonin receptor/CT-R Recombinant Antibody (SAA1757) (HB973013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CALCR/Calcitonin receptor/CT-R Recombinant Antibody (SAA1757) (HB973013)

概述

图片

参考文献

产品说明书

相关产品推荐

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