Human CALCR/Calcitonin receptor/CT-R Recombinant Protein (C-Fc) (HB973011)

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概述

货号	HB973011
品牌	abinScience
描述	Recombinant Human CALCR/Calcitonin receptor/CT-R Protein, C-Fc (HB973011) expressed in Mammalian Cells, spanning Ala25-Ile153. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	Mammalian cells
Accession号	P30988
蛋白长度	Ala25-Ile153
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	43.68 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	CALCR, CT-R, Calcitonin receptor
背景	Calcitonin receptor is a ~55 kDa protein. G protein-coupled receptor activated by ligand peptides amylin (IAPP), calcitonin (CT/CALCA) and calcitonin gene-related peptide type 1 (CGRP1/CALCA). CALCR interacts with receptor-activity-modifying proteins RAMP1, 2 and 3 to form receptor complexes AMYR1, 2 and 3, respectively. IAPP, CT and CGRP1 activate CALCR and AMYRs with distinct modes of receptor activation resulting in specific phenotypes. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. 1. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283 2. Cao, J. et al. (2024) Biochemistry 63, 1089-1096. PMID: 38603770 3. Moore, EE. et al. (1995) Molecular endocrinology (Baltimore, Md.) 9, 959-68. PMID: 7476993
Note	For research use only

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参考文献

产品说明书

Human CALCR/Calcitonin receptor/CT-R Recombinant Protein (C-Fc).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Human CALCR/Calcitonin receptor/CT-R Recombinant Protein (C-Fc) (HB973011)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Human CALCR/Calcitonin receptor/CT-R Recombinant Protein (C-Fc) (HB973011)

概述

图片

参考文献

产品说明书

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