Anti-Human Glypican 3 Recombinant Antibody (SAA0134), FITC (HW310117)

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货号	HW310117
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM, WB
宿主	Human
同种型	IgG1, kappa
克隆号	SAA0134
偶联物	FITC
克隆类型	Monoclonal
靶标	GPC3, MXR7, GTR2-2, Glypican-3, Intestinal protein OCI-5, OCI5
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Accession号	P51654
状态	Liquid
保存溶液	Liquid in PBS containing 0.2% BSA and 0.05% Proclin300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Glypican-3 (GPC3/Glypican 3) is a ~65 kDa protein. Cell surface proteoglycan. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway. 1. De Cat, B. et al. (2003) The Journal of cell biology 163, 625-35. PMID: 14610063 2. Capurro, MI. et al. (2005) The Journal of biological chemistry 280, 41201-6. PMID: 16227623 3. Capurro, M. et al. (2014) Journal of cell science 127, 1565-75. PMID: 24496449 4. Davoodi, J. et al. (2007) Proteomics 7, 2300-10. PMID: 17549790
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human Glypican 3 Recombinant Antibody (SAA0134), FITC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-Human Glypican 3 Recombinant Antibody (SAA0134), FITC (HW310117)

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参考文献

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实验相关试剂

Anti-Human Glypican 3 Recombinant Antibody (SAA0134), FITC (HW310117)

概述

图片

参考文献

产品说明书

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